Target identification and validation

For internal projects, Polyphor normally selects targets, which are known in the public domain and which are validated, at least in an in vivo model.

However, in a collaborative project with a Pharma partner, target validation can be an intermediate objective.

With Polyphor's technologies, a molecule which has PK properties suitable for observation of the expected therapeutic effect after parenteral administration can rapidly be obtained, even if the molecule is not yet optimized with respect to all ADMET properties.