Primary screening & protein expression
Assay formats and screening - Assay development capabilities
Polyphor has in-house expertise in assay development (primary and secondary assays) for a wide range of target classes, which are available for internal and collaborative projects. More information available on PDF.
Protein expression & purification
Polyphor has considerable expertise in effective construct design and protein expression; with E. coli, insect, yeast and mammalian cells allowing the expression of hard to handle targets. Outstanding expertise in mutant design to increase solubility, stability and crystallization properties of proteins is available internally and Polyphor can build on established skills in protein refolding, delivering crystal grade material, for a wide variety of targets.